By Thomas J. Anderson, William R. Miller (auth.), Robert B. Dickson, Marc E. Lippman (eds.)
The present quantity represents the fourth over a interval of 5 years in our sequence on Advances within the mobile and Molecular Biology of Breast melanoma. the 1st 3 volumes have been entitled Breast melanoma: mobile and Molecular Biology, Regulatory Mechanisms in Breast melanoma, and Genes, Oncogenes, and Hormones, respectively. all through this sequence, we have now attempted to take a large examine state of the art themes in simple technological know-how examine into breast melanoma. This test has led to a variety of subject matter, together with rodent and human version structures, oncogenes, suppressor genes, development elements, hormones, tumor-host interactions, and determinants of metastases. due to the fact our final quantity, learn in breast melanoma has persevered to continue at an explosive cost. we are hoping the present quantity will give you the reader with many of the pleasure felt by way of the editors and authors as we commence to appreciate this all-too-common illness. the 1st component to this ebook is dedicated to the fundamental tactics of proli feration, differentiation, and malignant development of breast melanoma. T.l. Anderson and W.R. Miller lead off with an in depth description of controls on proliferation within the general human breast and in breast melanoma. This bankruptcy strongly emphasizes pathological elements. the second one bankruptcy, via M.R. Stampfer and P. Yaswen, provides a corresponding perspective via a presentation of experiments with human mammary epithelial cells in tradition. the second one component of the publication emphasizes the genetic foundation for breast melanoma onset and malignant development. bankruptcy three, through M.-C. King and S.
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