Progress components in biology and medication Ciba starting place Symposium 116 Chairman: Sir Michael Stoker 1985 a huge present subject matter in biomedical learn is the law of development and improvement on the molecular and mobile point. associated with this is often the hunt for a way of controlling proliferative illnesses, specifically melanoma. during this symposium, key learn staff talk about the connection among development components, their particular mobilephone floor receptors, the mobile and viral oncogenes, and mitogenesis. The half that development components could play in malignant transformation, atherosclerosis, embryonic improvement and general and irregular haemopoiesis is debated. the most elements thought of listed here are epidermal development issue, platelet-derived progress issue, the haemopoietic progress elements, and nerve development issue (a non-mitogenic, neurotrophic factor). The emphasis of the symposium is at the molecular biology of progress elements and their receptors and the research of the intracellular occasions that stick with receptor-ligand interplay. particular subject matters contain the connection of the EGF receptor to the v-erb-B remodeling protein, the function of protein phosphorylation in progress keep an eye on, receptors for phorbol ester tumour promoters and their putative endogenous ligands, and a newly defined regulatory issue which either inhibits and stimulates phone progress. different Ciba starting place Symposia released through Pitman: No 113: Retinoids, differentiation and illness Chairman: M.B. Sporn 1985 ISBN zero 272 79813 four No 114: Fibrosis Chairman: A.J. Bailey 1985 ISBN zero 272 79814 2 No 117: Photoperiodism, melatonin and the pineal Chairman: R.V. brief 1985 ISBN zero 272 79821 five No 118: Biochemistry of macrophages Chairman: Z.A. Cohn 1985 ISBN zero 272 79822 three
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