Download E-books Count Down: Six Kids Vie for Glory at the World's Toughest Math Competition PDF

By Steve Olson

Each summer season six math whizzes chosen from approximately a half-million American kids compete opposed to the world’s most sensible challenge solvers on the foreign Mathematical Olympiad. Steve Olson the six 2001 contestants from the serious tryouts to the Olympiad’s nail-biting ultimate rounds to find not just what drives those striking children yet what makes them either targeted and ordinary. within the procedure he offers attention-grabbing insights into the technological know-how of intelligence and studying and, eventually, the character of genius.
incredible, yet defying the entire math-nerd stereotypes, those kids are looking to excel in no matter what piques their interest, and they're involved in virtually every little thing — tune, video games, politics, activities, literature. One group member is ardent approximately either water polo and artistic writing. one other performs 4 musical tools. For enjoyable and leisure in the course of breaks, the Olympians invent video games of mind-boggling hassle. although pushed by way of the honor of successful this final math contest, they're in lots of methods no longer so diversified from different young ones, discovering natural pleasure in indulging their own passions. past the the Olympiad, Olson sheds gentle on many questions, from why american citizens believe so queasy approximately math, to why so few women compete within the topic, as to if or now not expertise is innate. contained in the cavernous gymnasium the place the contest occurs, count number Down uncovers a desirable culture and its attractive, pushed inhabitants.

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Download E-books Allergy Frontiers: Epigenetics, Allergens and Risk Factors PDF

By U. Wahn (auth.), Ruby Pawankar, Stephen T. Holgate, Lanny J. Rosenwasser (eds.)

When I entered the sphere of allergic reaction within the early Seventies, the traditional textbook used to be a couple of hundred pages, and the distinctiveness was once so compact that texts have been frequently authored fullyyt by means of a unmarried person and have been by no means better than one quantity. examine this with hypersensitivity Frontiers: Epigenetics, Allergens, and threat components, the current s- quantity textual content with good over a hundred and fifty participants from through the international. This publication captures the explosive development of our uniqueness because the single-author textbooks pointed out above. The remarkable structure of this paintings lies in its meticulous cognizance to element but entire scope. for instance, nice element is visible in manuscripts facing subject matters resembling “Exosomes, obviously taking place minimum antigen offering devices” and “Neuropeptide S receptor 1 (NPSR1), an bronchial asthma susceptibility gene.” The scope is exemplified by means of the original method of sickness entities in most cases handled in one bankruptcy in so much texts. for instance, anaphylaxis, a subject matter frequently limited to at least one bankruptcy in such a lot textbooks, is given 5 chapters in hypersensitive reaction Frontiers. This process permits the textual content to hire a number of participants for a unmarried subject, giving the reader the good thing about being brought to a couple of vi- element relating to a unmarried disease.

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Download E-books Marine Genomics: Methods and Protocols (Methods in Molecular Biology) PDF

This quantity offers the newest protocols for either laboratory and bioinformatics established analyses within the box of marine genomics. The chapters awarded within the ebook disguise a variety of issues, together with the sampling and genomics of bacterial groups, DNA extraction in marine organisms, high-throughput sequencing of entire mitochondrial genomes, phylogenomics, SNP discovery, SNP-arrays for species identity, electronic PCR-based quantification tools, surroundings DNA for invasive species surveillance and tracking, microarrays for the detection of waterborne pathogens, DNA barcoding of marine biodiversity, metabarcoding protocols for marine eukaryotes, analytical protocols for the visualization of eukaryotic variety, and purposes for genomic facts to benthic indices for environmental tracking. Written within the hugely successful Methods in Molecular Biology sequence structure, chapters contain creation to their respective subject matters, lists of the required fabrics and reagents, step by step, effectively reproducible laboratory protocols, and pointers on troubleshooting and warding off recognized pitfalls.

Cutting-edge and thorough, Marine Genomics: tools and Protocols is a beneficial source for researchers, scholars, and coverage makers within the box of marine biology.

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Download E-books Genetics of the Mouse PDF

This e-book, written by means of skilled geneticists, covers themes starting from the normal background of the mouse species, its dealing with and replica within the laboratory, and its classical genetics and cytogenetics, to trendy matters together with the research of the transcriptome, the parental imprinting and X-chromosome inactivation. The ideas for growing all types of mutations, both by means of genetic engineering or through the use of mutagens, also are reviewed and mentioned intimately. ultimately, a final bankruptcy outlines the technique used for the research of complicated or quantitative traits.


The authors additionally speak about the significance of exact phenotyping, that is now played within the mouse clinics confirmed world wide and determine the boundaries of the mouse version, which lower than convinced conditions can fail to provide the phenotype anticipated from the cognate within the human version. for every bankruptcy an up to date record of pertinent references is equipped.


In brief, this ebook deals an important source for all scientists who use or plan to take advantage of mice of their research.

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Download E-books Chemical Genomics and Proteomics, Second Edition PDF

Since the ebook of the pioneering first variation of Chemical Genomics and Proteomics greater than seven years in the past, the world of chemical genomics has speedily elevated and assorted to various novel equipment and subdisciplines, akin to chemical glycomics and lipidomics. This moment variation has been up-to-date to uniquely mirror this interdisciplinary characteristic in addition to the striking advancements that experience happened. the recent version additionally covers cutting edge purposes from cellphone biology to drug discovery to, extra lately, scientific diagnostics and scientific perform, which make the most of the recommendations of chemical genomics.

The textual content presents an summary of the innovations and methodologies of chemical genomics, targeting rising applied sciences and up to date functions within the components of blend chemical genetics, toxicogenomics, drug chemical genomics and proteomics, and orthogonal chemical genetics. It describes the advance and alertness of novel analytical tools utilized in lipodomics, corresponding to steroidomics. The booklet additionally discusses biomarker discovery purposes of microarray applied sciences utilizing DNA, RNA, and protein and glycan arrays. Chapters conceal extra purposes of biomolecular biomarkers for sickness prognosis, in small molecule drug R&D, and through healing use of medications. those contain prognostic, disorder particular, reaction (surrogate), and toxicity biomarkers.

In addition, the textual content explores the rules of latest platforms biology and genomics in experimental medicine―a new paradigm that demonstrates a network-oriented view and complex statistical and informatics information administration, establishing the way in which towards custom-made drugs. eventually, a variety of in silico chemogenomics methods are addressed for predicting binding of drug applicants to bad objectives, which might assist in designing higher scientific applicants with fewer unintended effects. This re-creation merits a vast variety of readers from business and educational researchers in drug discovery, medicinal chemistry, and molecular and mobile biology to physicians in scientific diagnostics and scholars in similar fields of study.

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Download E-books The Cute and the Cool: Wondrous Innocence and Modern American Children's Culture PDF

The 20 th century used to be, through any reckoning, the age of the kid in the US. this day, we pay homage on the altar of formative years, heaping unending items at the younger, reveling in stories of a extra blameless time, and discovering solace within the softly backlit stories of our earliest years. we're, the proclamation is going, simply significant youngsters at middle. And, for this reason, we enjoy prolonging and inflating the formative years studies of our offspring. In photos of the naughty yet great Buster Brown and the coquettish yet candy Shirley Temple, americans at mid-century provided up a gorgeous international of treats, toys, and tales, making a new photo of the kid as "cute." vacation trips similar to Christmas and Halloween grew to become blockbuster affairs, autos to gas the bedazzled and wondrous innocence of the lovable baby. All this, Gary pass illustrates, mirrored the preoccupations of a extra mild and prosperous tradition, however it additionally served to disencumber adults from their rational and sometimes tedious worlds of labor and accountability. yet difficulty quickly entered paradise. The "cute" changed into "cool" as little ones, following their parental instance, embraced the reward of delusion and unrestrained wish to insurgent opposed to the saccharine excesses of wondrous innocence in planned pursuit of the anti-cute. videos, comedian books, and games beckoned to young ones with the allures of a regularly violent, sexualized, and more and more harsh worldview. Unwitting and resistant accomplices to this advertisement transformation of early life, adults sought-over and another time, in repeated and predictable cycles-to rein in those threats in a mostly futile jeremiad to maintain the outdated order. therefore, the lovable child-deliberately synthetic and cultivated--has paradoxically fostered a profoundly ambivalence towards early life and baby rearing this day. Expertly weaving his method during the cultural artifacts, advertisement currents, and parenting anxieties of the former century, Gary move bargains a colourful and completely clean portrait of the forces that experience outlined American childhood.

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Download E-books Proteomic and Genomic Analysis of Cardiovascular Disease PDF

This can be the first actual publication to target this new strategy that may finally reduction in constructing new diagnostic markers and treatments for controlling and treating middle illness - the number-one killer within the industrialized international. Divided into elements, the e-book describes not just the potentials, but additionally the constraints of those applied sciences. The editors, either renowned in the medical neighborhood, supply new insights into the biochemical and mobile mechanisms of heart problems, in addition to masking the transition into scientific functions. In so doing, they spotlight a number of the innovations and technical facets in order to support the transforming into variety of researchers meaning to make the most of those techniques. the result's a good approach of teaching and informing graduate scholars, post-doctoral fellows in addition to researchers in academia and in regards to the newest advancements during this quarter.

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